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Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight loss and the people who go through it you need to err to the side of caution and allow FDA do its job and demand some investigation be done so the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on their medications.

Researchers found out that participants investing in this drug for a year, lost weight within a month and have kept the extra weight off through the entire 56 weeks with the study. Contrave is really a combination from the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of several active ingredient, which can make them more efficient and safer.

Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular may be the fact that since right now there aren't long term prescription diet pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug can also raise hypertension and heart rate, and shouldn't be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must 't be used in patients with uncontrolled high blood pressure levels, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.

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